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ETHANOL EXTRACT OF BINAHONG LEAVES EFFECT (Anredera cordifolia (Ten.) Steen) ON HEMATOLOGYCAL CHANGES IN FEMALE WISTAR RATS

Proceeding from jhptump / 2018-09-03 11:52:52
Oleh : Silma Kaffah, Fitri Kurniwati, Anjar Mahardian Kusuma, Asmiyenti Djaliasrin Djalil, Universitas Muhammadiyah Purwokerto
Dibuat : 2018-09-03, dengan 2 file

Keyword : hematology, ethanol extract, binahong leaves (Anredera cordifolia(Teen.)Steen), white female rats

Binahong (Anredera cordifolia(Teen.)Steen) is one of the plant that can be used for several diseases. This research has been conducted which explore the effect of ethanol extract of binahong leaves (Anredera cordifolia (Ten.)Steen) on hematological changes in female wistar rats. Animal tests are selected using a complete randomized block design, which is the test animals were randomly selected and have the same opportunity to be treated. Sighting study were conducted to determine the dose used in the main study. Doses used in the sighting study was 300 mg/kg and 2000 mg/kg, in this test there is no death in animal test trials. Animal test divided into 2 groups: the treatment and the control group. Each

group consisted of 5 animals tested, which is the treatment group was given a dose of 2000 mg/kg and the control group was given distilled water. results analysis Independent T test show that ethanol extract of binahong leaves did not affect the value of hematological (erythrocytes,leukocytes). On the other hand the results analysis used Dependent T test show that there is changes in the number of hematological (erythrocytes and leukocytes) in the treatment group on D-1 versus D+1, D-1 versus D+7 and D-1 versus D+14. That

different might not by administration of test preparation, because the control group also show changes the number of erythrocytes and leukocytes at the same time measurement.

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