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Antimicrobial Activity of Extracts and Fractions of Purwoceng (Pimpinella alpina Molk)

Proceeding from jhptump / 2018-02-20 13:57:13
Oleh : Retno Wahyuningrum, Universitas Muhammadiyah Purwokerto (
Dibuat : 2018-02-20, dengan 2 file

Keyword : Antimicrobial activity, Purwoceng (Pimpinella alpina Molk)

Purwoceng (Pimpinella alpina Molk) is a traditional aphrodisiac plant. This plant is originated from Indonesia and grow at Dieng Plateu, Central Java. The antimicrobial activity of petroleum ether extract, ethyl acetate extract, ethanol extract and fractions of ethyl acetate extract were assayed in vitro by agar disc diffusion method against Staphyloccus aureus, Escherichia coli, MG42 bacterial isolate, Candida albicans and Malassezia furfur. Ciprofloxacin was used as positive control in antibacterial assay and Dimethylsolfoxide (DMSO) was used as negative control. Ethyl acetat extract and etanol extract of Purwoceng have antibacterial activity against Staphylococcus aureus, Escherichia coli, and MG42 bacterial isolate. None of the extracts and fractions of Purwoceng assayed was active against C. albicans. All of the extracts were active against M. furfur. The lowest concentration of ethyl acetate extract inhibiting M. furfur was 1.25%.

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